Weekend getaways from Des Moines
18 cities you can fly to nonstop on Friday and back nonstop on Sunday. 8 of them have a Friday flight at 5pm or later — leave after work.
Under 2 hours · 12
| Destination | Out Friday | Back Sunday |
|---|---|---|
| FSD — Sioux Falls ~37m · Allegiant Find fares 🥕 | 1 flightlast 11:33a | 1 flightlast 12:50a |
| MSP — Minneapolis ~40m · Alaska, Delta Find fares 🥕 | 5 flightslast 8:14p | 4 flightslast 8:33p |
| MDW — Chicago ~51m · Southwest Find fares 🥕 | 2 flightslast 3:54p | 2 flightslast 10:31p |
| ORD — Chicago ~55m · American, United Find fares 🥕 | 11 flightslast 8:07p | 11 flightslast 11:43p |
| FAR — Fargo ~57m · Allegiant Find fares 🥕 | 1 flightlast 2:04p | 1 flightlast 12:32a |
| DTW — Detroit ~1h16m · Delta Find fares 🥕 | 3 flightslast 5:48p | 3 flightslast 8:20p |
| DEN — Denver ~1h23m · Frontier, Southwest, United Find fares 🥕 | 8 flightslast 11:32p | 8 flightslast 10:16p |
| DFW — Dallas-Fort Worth ~1h33m · American Find fares 🥕 | 4 flightslast 6:30p | 5 flightslast 10:33p |
| ATL — Atlanta ~1h39m · Delta Find fares 🥕 | 4 flightslast 6:53p | 4 flightslast 9:21p |
| DCA — Washington ~1h46m · American Find fares 🥕 | 2 flightslast 2:22p | 2 flightslast 10:14p |
| IAH — Houston ~1h49m · United Find fares 🥕 | 2 flightslast 3:48p | 2 flightslast 8:07p |
| CLT — Charlotte ~1h52m · American Find fares 🥕 | 2 flightslast 1:30p | 2 flightslast 10:36p |
2 to 4 hours · 6
| Destination | Out Friday | Back Sunday |
|---|---|---|
| PHL — Philadelphia ~2h6m · American, Allegiant Find fares 🥕 | 2 flightslast 1:12p | 3 flightslast 11:08p |
| LGA — New York ~2h16m · American, Delta Find fares 🥕 | 2 flightslast 7:29a | 2 flightslast 8:13p |
| SLC — Salt Lake City ~2h17m · American, Alaska, Delta Find fares 🥕 | 1 flightlast 1:54p | 1 flightlast 9:34a |
| LAS — Las Vegas ~2h50m · Allegiant, Southwest Find fares 🥕 | 2 flightslast 8:47p | 2 flightslast 5:20p |
| PHX — Phoenix ~2h51m · American Find fares 🥕 | 2 flightslast 2:29p | 3 flightslast 7:57p |
| LAX — Los Angeles ~3h36m · American Find fares 🥕 | 1 flightlast 7:00p | 1 flightlast 12:56p |
Nonstop weekend trips from Des Moines (DSM)
These are the destinations with nonstop flights out of DSM on Fridays and nonstop flights back on Sundays, both observed in our recent sample of departures. Times are local to each departure airport; "last" is the latest departure that day.
Only destinations whose return flights we track are listed — 28 of the 48 cities with nonstops from DSM. A destination that is missing may still have Sunday flights back; check its route page. All 48 nonstops from Des Moines →
Route data updated October 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
Where can I fly nonstop from Des Moines for a weekend?
18 destinations have nonstop flights out of Des Moines (DSM) on Friday and back on Sunday, including Sioux Falls, Minneapolis, Chicago, Chicago, Fargo and Detroit. 8 of them have a Friday departure at 5pm or later.
What are the shortest weekend flights from Des Moines?
Sioux Falls (about 37m), Minneapolis (about 40m) and Chicago (about 51m) are the quickest nonstop weekend trips from DSM, based on recently observed departures.