Direct flights from Chicago to Des Moines
67 nonstop flights a week on 2 airlines. Zero layovers — one hop from ORD to DSM.
Flight time: about 52m nonstop
Which days does it fly?
When does it fly?
Departure times in Chicago local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| SkyWest SKW4955 | 7:22a | 53m | Fri |
| SkyWest SKW4955 | 7:34a | 54m | Wed |
| SkyWest SKW4955 | 7:35a | 1h2m | Tue |
| SkyWest SKW4955 | 7:53a | 45m | Sun |
| SkyWest SKW4955 | 8:52a | 1h3m | Thu |
| United UAL530 | 9:22a | 52m | Mon |
| United UAL530 | 9:26a | 50m | Wed, Fri |
| United UAL530 | 9:47a | 54m | Sun |
| United UAL530 | 10:27a | 1h3m | Tue |
| SkyWest SKW5411 | 11:03a | 52m | Wed–Thu |
| SkyWest SKW5411 | 11:19a | 58m | Mon, Fri, Sun |
| SkyWest SKW4955 | 11:36a | 55m | Sat |
| SkyWest SKW4955 | 11:52a | 53m | Mon |
| United UAL530 | 11:55a | 54m | Sat |
| SkyWest SKW5411 | 12:04p | 58m | Tue |
| SkyWest SKW5411 | 12:12p | 58m | Sat |
| SkyWest SKW4933 | 12:39p | 54m | Wed |
| SkyWest SKW4933 | 12:53p | 54m | Mon |
| SkyWest SKW4933 | 12:56p | 1h3m | Fri |
| United UAL530 | 12:59p | 45m | Thu |
| United UAL2836 | 1:10p | 54m | Mon, Wed, Fri |
| SkyWest SKW4933 | 1:31p | 51m | Sat |
| United UAL2836 | 1:32p | 45m | Sun |
| SkyWest SKW4933 | 2:00p | 48m | Tue, Sun |
| United UAL2836 | 2:46p | 45m | Tue |
| Republic Airways RPA4769 | 4:00p | 41m | Mon, Sun |
| Republic Airways RPA4769 | 4:22p | 39m | Fri |
| Republic Airways RPA4769 | 4:29p | 37m | Wed |
| Republic Airways RPA4769 | 4:41p | 59m | Thu |
| United UAL1121 | 4:45p | 44m | Mon |
| United UAL2836 | 4:47p | 44m | Thu |
| United UAL1121 | 5:25p | 45m | Sun |
| Republic Airways RPA4769 | 5:28p | 59m | Sat |
| United UAL1121 | 5:42p | 44m | Tue, Fri |
| SkyWest SKW4890 | 6:00p | 57m | Sun |
| Republic Airways RPA4769 | 6:11p | 40m | Tue |
| SkyWest SKW4890 | 6:29p | 53m | Fri |
| SkyWest SKW4890 | 6:50p | 55m | Wed |
| United UAL1121 | 6:58p | 44m | Wed |
| SkyWest SKW4890 | 7:23p | 46m | Mon |
| SkyWest SKW4890 | 7:38p | 54m | Tue, Thu |
| United UAL2800 | 8:25p | 44m | Mon |
| United UAL2800 | 8:36p | 54m | Sun |
| United UAL1121 | 9:10p | 44m | Thu |
| United UAL2800 | 9:11p | 44m | Wed |
| United UAL2800 | 9:25p | 44m | Tue |
| United UAL2800 | 9:47p | 44m | Sat |
| United UAL2800 | 10:04p | 55m | Fri |
| Republic Airways RPA4402 | 10:49p | 41m | Wed, Sat, Sun |
| Republic Airways RPA4402 | 10:58p | 39m | Fri |
| Republic Airways RPA4402 | 11:28p | 32m | Tue, Thu |
| United UAL2800 | 11:38p | 50m | Thu |
| Republic Airways RPA4402 | 11:39p | 57m | Mon |
American
UnitedThe route
One hop: ORD → DSMDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Chicago (ORD) to Des Moines (DSM)
Chicago O'Hare International Airport (ORD) has 67 nonstop flights a week to Des Moines (DSM), operated by American and United. No layovers, no connections — one hop out of ORD and you're there.
This route flies every day of the week, so any travel day works. Route data updated September 2026 from observed departures.
Route data updated September 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Chicago to Des Moines?
The nonstop flight from Chicago (ORD) to Des Moines (DSM) takes about 52m in the air, based on recently observed nonstop departures.
How long does it take to drive from Chicago to Des Moines?
Driving from Chicago to Des Moines takes about 4h 58m, covering roughly 334 miles. The nonstop flight takes about 52m.