Direct flights from Denver to Des Moines
52 nonstop flights a week on 3 airlines. Zero layovers — one hop from DEN to DSM.
Flight time: about 1h18m nonstop
Which days does it fly?
When does it fly?
Departure times in Denver local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| United UAL1548 | 1:03a | 1h38m | Sat |
| Southwest SWA8505 | 5:05a | 1h30m | Tue |
| SkyWest SKW5130 | 7:43a | 1h18m | Sat |
| Frontier FFT1678 | 8:01a | 1h17m | Thu |
| SkyWest SKW5361 | 8:06a | 1h19m | Mon, Tue, Sun |
| SkyWest SKW5361 | 8:17a | 1h19m | Wed–Fri |
| Frontier FFT1678 | 9:01a | 1h13m | Sun |
| United UAL596 | 9:54a | 1h20m | Tue, Thu |
| United UAL596 | 9:55a | 1h14m | Wed, Fri, Sun |
| United UAL596 | 10:10a | 1h14m | Mon |
| United UAL596 | 10:27a | 1h16m | Sat |
| Southwest SWA200 | 11:22a | 1h26m | Mon |
| Southwest SWA200 | 11:25a | 1h28m | Thu |
| Southwest SWA379 | 11:30a | 1h26m | Wed |
| Southwest SWA3425 | 11:36a | 1h28m | Sat |
| Southwest SWA200 | 11:43a | 1h27m | Fri |
| Southwest SWA379 | 12:07p | 1h11m | Tue |
| Southwest SWA295 | 1:37p | 1h26m | Sun |
| United UAL1311 | 1:42p | 1h16m | Wed–Thu |
| United UAL1311 | 1:48p | 1h18m | Mon, Sat, Sun |
| United UAL1311 | 2:09p | 1h14m | Tue |
| United UAL1311 | 2:38p | 1h15m | Fri |
| Frontier FFT1678 | 4:51p | 1h12m | Mon |
| United UAL549 | 5:50p | 1h16m | Tue, Thu |
| United UAL549 | 6:01p | 1h10m | Mon, Sun |
| United UAL549 | 6:06p | 1h14m | Wed |
| Southwest SWA161 | 6:19p | 1h24m | Tue |
| Southwest SWA161 | 6:33p | 1h25m | Sat |
| Southwest SWA3485 | 7:03p | 1h27m | Sun |
| Frontier FFT1678 | 7:20p | 1h16m | Fri |
| Southwest SWA161 | 7:22p | 1h30m | Wed |
| Southwest SWA3425 | 8:06p | 1h28m | Thu–Fri |
| United UAL1548 | 8:54p | 1h16m | Tue |
| United UAL1548 | 9:10p | 1h14m | Mon, Wed, Sat |
| United UAL549 | 9:38p | 1h14m | Fri |
| United UAL1548 | 10:05p | 1h14m | Sun |
| United UAL1548 | 10:28p | 1h18m | Thu |
Southwest
UnitedThe route
One hop: DEN → DSMDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Denver (DEN) to Des Moines (DSM)
Denver International Airport (DEN) has 52 nonstop flights a week to Des Moines (DSM), operated by Frontier, Southwest and United. No layovers, no connections — one hop out of DEN and you're there.
This route flies every day of the week, so any travel day works. Route data updated September 2026 from observed departures.
Route data updated September 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Denver to Des Moines?
The nonstop flight from Denver (DEN) to Des Moines (DSM) takes about 1h18m in the air, based on recently observed nonstop departures.
How long does it take to drive from Denver to Des Moines?
Driving from Denver to Des Moines takes about 9h 34m, covering roughly 671 miles. The nonstop flight takes about 1h18m.