Direct flights from Des Moines to Phoenix
16 nonstop flights a week on 1 airline. Zero layovers — one hop from DSM to PHX.
Flight time: about 2h51m nonstop
Which days does it fly?
When does it fly?
Departure times in Des Moines local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| American SKW6271 | 5:31a | 2h40m | Wed |
| American SKW6271 | 5:41a | 2h49m | Mon, Tue, Thu, Fri, Sat, Sun |
| American SKW6262 | 2:29p | 2h52m | Mon, Wed, Fri |
| American SKW6262 | 2:38p | 2h52m | Tue |
| American SKW6262 | 3:13p | 2h33m | Thu |
| American SKW6262 | 3:28p | 2h52m | Sun |
| American SKW6262 | 3:42p | 2h52m | Sat |
| American ENY4138 | 5:41p | 2h32m | Thu, Sun |
American
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The route
One hop: DSM → PHXDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Des Moines (DSM) to Phoenix (PHX)
Des Moines International Airport (DSM) has 16 nonstop flights a week to Phoenix (PHX), operated by American. No layovers, no connections — one hop out of DSM and you're there.
This route flies every day of the week, so any travel day works. Route data updated October 2026 from observed departures.
Route data updated October 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Des Moines to Phoenix?
The nonstop flight from Des Moines (DSM) to Phoenix (PHX) takes about 2h51m in the air, based on recently observed nonstop departures.
How long does it take to drive from Des Moines to Phoenix?
Driving from Des Moines to Phoenix takes about 21h 23m behind the wheel — roughly 1,399 miles, or about 2 days of real driving. The nonstop flight takes about 2h51m.