Direct flights from Phoenix to Des Moines
17 nonstop flights a week on 2 airlines. Zero layovers — one hop from PHX to DSM.
Flight time: about 2h18m nonstop
Which days does it fly?
When does it fly?
Departure times in Phoenix local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| SkyWest SKW6374 | 8:44a | 2h9m | Mon |
| SkyWest SKW6374 | 8:50a | 2h10m | Sat–Sun |
| SkyWest SKW6374 | 8:57a | 2h12m | Fri |
| SkyWest SKW6374 | 9:11a | 2h37m | Wed |
| SkyWest SKW6374 | 9:16a | 2h15m | Tue, Thu |
| American ENY4138 | 12:29p | 2h30m | Thu, Sun |
| Southwest SWA3228 | 2:00p | 2h32m | Thu |
| SkyWest SKW4950 | 7:17p | 2h20m | Tue, Wed, Fri, Sat |
| SkyWest SKW4950 | 7:25p | 2h24m | Mon, Thu |
| SkyWest SKW4950 | 7:57p | 2h8m | Sun |
American
SouthwestThe route
One hop: PHX → DSMDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Phoenix (PHX) to Des Moines (DSM)
Phoenix Sky Harbor International Airport (PHX) has 17 nonstop flights a week to Des Moines (DSM), operated by American and Southwest. No layovers, no connections — one hop out of PHX and you're there.
This route flies every day of the week, so any travel day works. Route data updated October 2026 from observed departures.
Route data updated October 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Phoenix to Des Moines?
The nonstop flight from Phoenix (PHX) to Des Moines (DSM) takes about 2h18m in the air, based on recently observed nonstop departures.
How long does it take to drive from Phoenix to Des Moines?
Driving from Phoenix to Des Moines takes about 21h 23m behind the wheel — roughly 1,399 miles, or about 2 days of real driving. The nonstop flight takes about 2h18m.