Direct flights from Des Moines to Chicago
76 nonstop flights a week on 2 airlines. Zero layovers — one hop from DSM to ORD.
Flight time: about 55m nonstop
Which days does it fly?
When does it fly?
Departure times in Des Moines local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Republic Airways RPA3456 | 6:09a | 46m | Thu |
| SkyWest SKW6024 | 6:10a | 58m | Tue, Sat |
| SkyWest SKW6024 | 6:16a | 58m | Mon, Wed |
| SkyWest SKW6024 | 6:58a | 58m | Fri |
| Republic Airways RPA4383 | 7:12a | 59m | Mon, Wed |
| Republic Airways RPA4383 | 7:20a | 54m | Thu–Fri |
| Republic Airways RPA4383 | 7:43a | 20m | Sat |
| United UAL2668 | 8:01a | 54m | Mon–Tue |
| United UAL2668 | 8:08a | 52m | Wed, Fri |
| Republic Airways RPA4383 | 8:13a | 58m | Sun |
| United UAL2668 | 8:16a | 56m | Thu, Sun |
| United UAL2668 | 8:34a | 52m | Sat |
| SkyWest SKW4955 | 10:44a | 1h6m | Thu |
| SkyWest SKW4955 | 10:46a | 1h6m | Mon, Tue, Fri, Sat |
| SkyWest SKW4955 | 10:58a | 54m | Wed |
| Republic Airways RPA4383 | 11:03a | 24m | Tue |
| United UAL2769 | 11:31a | 55m | Mon–Tue |
| United UAL2769 | 11:40a | 55m | Wed, Sat |
| United UAL2769 | 11:50a | 52m | Thu–Fri |
| SkyWest SKW6040 | 1:29p | 58m | Tue |
| SkyWest SKW6040 | 1:39p | 58m | Wed–Fri |
| SkyWest SKW6040 | 1:51p | 58m | Sat |
| SkyWest SKW6040 | 2:34p | 58m | Mon |
| SkyWest SKW4933 | 2:37p | 56m | Mon, Wed |
| SkyWest SKW4933 | 2:53p | 54m | Sat |
| SkyWest SKW4955 | 2:56p | 1h2m | Sun |
| SkyWest SKW4933 | 2:56p | 1h5m | Tue, Thu, Fri |
| United UAL312 | 3:18p | 51m | Mon, Wed, Fri |
| United UAL312 | 3:29p | 57m | Sat |
| SkyWest SKW4933 | 3:41p | 1h5m | Sun |
| United UAL312 | 3:44p | 55m | Tue |
| SkyWest SKW6040 | 4:00p | 50m | Sun |
| United UAL2769 | 4:07p | 49m | Sun |
| United UAL312 | 4:34p | 55m | Thu |
| United UAL312 | 5:12p | 51m | Sun |
| Republic Airways RPA4769 | 6:02p | 42m | Mon, Tue, Sat |
| Republic Airways RPA4769 | 6:21p | 54m | Wed–Thu |
| Republic Airways RPA4769 | 6:37p | 47m | Fri |
| United UAL2770 | 6:59p | 1h1m | Tue |
| United UAL2770 | 7:10p | 57m | Mon |
| United UAL2770 | 7:22p | 56m | Thu–Fri |
| United UAL2770 | 7:48p | 1h | Wed |
| SkyWest SKW4928 | 7:54p | 54m | Tue |
| SkyWest SKW4928 | 8:07p | 49m | Mon, Fri, Sat |
| SkyWest SKW4928 | 8:20p | 54m | Thu |
| United UAL2770 | 8:23p | 54m | Sat–Sun |
| Republic Airways RPA4769 | 8:51p | 5m | Sun |
| SkyWest SKW4928 | 9:28p | 46m | Wed |
| SkyWest SKW4928 | 10:20p | 54m | Sun |
American
UnitedThe route
One hop: DSM → ORDDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Des Moines (DSM) to Chicago (ORD)
Des Moines International Airport (DSM) has 76 nonstop flights a week to Chicago (ORD), operated by American and United. No layovers, no connections — one hop out of DSM and you're there.
This route flies every day of the week, so any travel day works. Route data updated October 2026 from observed departures.
Route data updated October 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Des Moines to Chicago?
The nonstop flight from Des Moines (DSM) to Chicago (ORD) takes about 55m in the air, based on recently observed nonstop departures.
How long does it take to drive from Des Moines to Chicago?
Driving from Des Moines to Chicago takes about 4h 58m, covering roughly 334 miles. The nonstop flight takes about 55m.