Direct flights from Des Moines to Minneapolis
27 nonstop flights a week on 1 airline. Zero layovers — one hop from DSM to MSP.
Flight time: about 43m nonstop
Which days does it fly?
When does it fly?
Departure times in Des Moines local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Delta EDV5402 | 7:12a | 46m | Mon, Sat, Sun |
| Delta EDV5402 | 7:20a | 42m | Thu–Fri |
| Delta EDV5402 | 8:44a | 41m | Tue |
| Delta EDV5402 | 9:13a | 43m | Wed |
| Delta EDV4998 | 11:01a | 43m | Mon, Thu, Sat, Sun |
| Delta EDV4998 | 11:09a | 42m | Wed |
| Delta EDV4998 | 11:15a | 53m | Fri |
| Delta EDV4998 | 11:57a | 37m | Tue |
| Delta EDV5490 | 2:50p | 38m | Tue, Fri |
| Delta EDV5490 | 3:01p | 43m | Mon, Thu, Sun |
| Delta EDV5490 | 3:58p | 37m | Wed |
| Delta EDV5020 | 6:02p | 42m | Mon–Fri |
| Delta EDV5020 | 6:21p | 43m | Sun |
| Delta EDV5020 | 6:32p | 57m | Sat |
Delta
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The route
One hop: DSM → MSPDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Des Moines (DSM) to Minneapolis (MSP)
Des Moines International Airport (DSM) has 27 nonstop flights a week to Minneapolis (MSP), operated by Delta. No layovers, no connections — one hop out of DSM and you're there.
This route flies every day of the week, so any travel day works. Route data updated July 2026 from observed departures.
Route data updated July 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Des Moines to Minneapolis?
The nonstop flight from Des Moines (DSM) to Minneapolis (MSP) takes about 43m in the air, based on recently observed nonstop departures.
How long does it take to drive from Des Moines to Minneapolis?
Driving from Des Moines to Minneapolis takes about 3h 35m — roughly 244 miles — so the car is a real alternative on this route. The nonstop flight takes about 43m.