Direct flights from Minneapolis to Des Moines
28 nonstop flights a week on 2 airlines. Zero layovers — one hop from MSP to DSM.
Flight time: about 41m nonstop
Which days does it fly?
When does it fly?
Departure times in Minneapolis local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Delta EDV5253 | 7:34a | 40m | Tue |
| Delta EDV4998 | 9:11a | 40m | Sat |
| Delta EDV4998 | 9:21a | 44m | Tue, Wed, Fri |
| Delta EDV4998 | 9:28a | 38m | Thu, Sun |
| Delta EDV4998 | 9:36a | 39m | Mon |
| Delta EDV5490 | 1:09p | 37m | Mon, Tue, Wed, Sat, Sun |
| Delta EDV5490 | 1:17p | 55m | Fri |
| Delta EDV5490 | 3:23p | 40m | Thu |
| Delta EDV4913 | 3:48p | 44m | Tue, Thu, Fri, Sun |
| Delta EDV4913 | 4:20p | 45m | Wed |
| Alaska ASA9728 | 5:51p | 42m | Sat |
| Delta EDV4913 | 6:59p | 39m | Mon |
| Delta EDV5253 | 8:11p | 41m | Tue, Fri, Sat |
| Delta EDV5253 | 8:33p | 50m | Wed, Sun |
| Delta EDV5253 | 9:01p | 42m | Thu |
DeltaThe route
One hop: MSP → DSMDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Minneapolis (MSP) to Des Moines (DSM)
Minneapolis–Saint Paul International Airport / Wold–Chamberlain Field (MSP) has 28 nonstop flights a week to Des Moines (DSM), operated by Alaska and Delta. No layovers, no connections — one hop out of MSP and you're there.
This route flies every day of the week, so any travel day works. Route data updated October 2026 from observed departures.
Route data updated October 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Minneapolis to Des Moines?
The nonstop flight from Minneapolis (MSP) to Des Moines (DSM) takes about 41m in the air, based on recently observed nonstop departures.
How long does it take to drive from Minneapolis to Des Moines?
Driving from Minneapolis to Des Moines takes about 3h 35m — roughly 244 miles — so the car is a real alternative on this route. The nonstop flight takes about 41m.