Direct flights from St. Louis
58 nonstop destinations. Zero layovers, zero connections — just one hop out of STL.
Usually: Orlando (MCO), on Frontier
Frankfurt (FRA), 4,600 miles · 8 h 20 m
Where one hop gets you
Dashed arcs = nonstop routes from STL · updates with the day filterDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Hotels near STL with a free airport shuttle 14% of flights from STL leave before 7am
American
United
Southwest
Delta
Sun CountryFlight numbers from St. Louis (STL)
Each one's timetable, usual aircraft and how it ran in our sample — 12 of the 43 we cover from STL, flown most days first.
Where can you fly nonstop from St. Louis (STL)?
St. Louis Lambert International Airport (STL) offers nonstop flights to 58 destinations across the United States, Canada, Germany, Mexico and the United Kingdom. The busiest direct routes from STL are served by Southwest, American, Frontier and United, with the most frequent nonstop service to Chicago, Denver and Atlanta.
Headed abroad without a connection? STL has direct international flights to Cancun, Toronto and Montreal. Use the day filter above to see exactly which routes fly on the day you want to travel. Route data updated November 2026 from observed departures.
Usually the cheapest nonstop from St. Louis is to Orlando (MCO) on Frontier, then Las Vegas (LAS) on Frontier, then Charlotte (CLT) on Southwest.
Longest nonstop from St. Louis: Frankfurt (FRA), about 4,600 miles and 8 h 20 m.
Airlines and flight times at STL
11 airlines fly nonstop out of STL. Southwest runs the biggest operation — about 757 of the 1370 weekly departures (55%), across 46 routes — followed by American and United.
The airlines flying nonstop out of St. Louis are Southwest, American, United, Delta, Frontier, Alaska, Jazz (Air Canada Express), Southern Airways Express, Lufthansa, British Airways and Sun Country.
On 36 of St. Louis's 58 nonstop routes, a single airline has the service to itself — Southwest is the only airline with a nonstop to Dallas, and United the only one to Newark.
The shortest nonstop out of STL is Chicago (MDW) at about 42m in the air; the longest is Frankfurt at about 8h18m.
Route data updated November 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.