Direct flights from St. Louis to Fort Myers
16 nonstop flights a week on 1 airline. Zero layovers — one hop from STL to RSW.
Flight time: about 2h6m nonstop
Which days does it fly?
When does it fly?
Departure times in St. Louis local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Southwest SWA1110 | 5:58a | 2h7m | Thu |
| Southwest SWA3884 | 6:20a | 2h10m | Mon, Fri |
| Southwest SWA3884 | 10:24a | 2h5m | Sat |
| Southwest SWA3884 | 10:27a | 2h14m | Tue |
| Southwest SWA1282 | 10:30a | 2h4m | Sun |
| Southwest SWA3884 | 10:37a | 2h3m | Wed |
| Southwest SWA651 | 11:52a | 2h3m | Thu |
| Southwest SWA4074 | 4:34p | 2h3m | Sat |
| Southwest SWA22 | 4:38p | 2h16m | Sun |
| Southwest SWA4074 | 6:54p | 2h11m | Tue |
| Southwest SWA4074 | 7:06p | 2h10m | Mon, Wed |
| Southwest SWA4074 | 7:26p | 2h2m | Fri |
| Southwest SWA4074 | 7:48p | 2h11m | Sun |
| Southwest SWA4074 | 8:05p | 2h5m | Thu |
Southwest
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The route
One hop: STL → RSWDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from St. Louis (STL) to Fort Myers (RSW)
St. Louis Lambert International Airport (STL) has 16 nonstop flights a week to Fort Myers (RSW), operated by Southwest. No layovers, no connections — one hop out of STL and you're there.
This route flies every day of the week, so any travel day works. Route data updated October 2026 from observed departures.
Route data updated October 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from St. Louis to Fort Myers?
The nonstop flight from St. Louis (STL) to Fort Myers (RSW) takes about 2h6m in the air, based on recently observed nonstop departures.
How long does it take to drive from St. Louis to Fort Myers?
Driving from St. Louis to Fort Myers takes about 16h 28m behind the wheel — roughly 1,129 miles, or about 2 days of real driving. The nonstop flight takes about 2h6m.