Direct flights from St. Louis to Boston
32 nonstop flights a week on 2 airlines. Zero layovers — one hop from STL to BOS.
Flight time: about 2h22m nonstop
Which days does it fly?
When does it fly?
Departure times in St. Louis local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Southwest SWA863 | 6:07a | 2h7m | Thu |
| Southwest SWA4061 | 7:08a | 2h22m | Fri |
| Southwest SWA4061 | 8:02a | 2h30m | Mon |
| Southwest SWA3808 | 8:27a | 2h29m | Sun |
| American ENY3546 | 8:56a | 2h13m | Wed |
| American ENY3546 | 9:06a | 2h13m | Fri |
| American ENY3546 | 9:20a | 2h18m | Tue, Thu |
| Southwest SWA3808 | 10:24a | 2h26m | Sat |
| Southwest SWA1538 | 10:52a | 2h27m | Wed |
| Southwest SWA1538 | 10:57a | 2h27m | Tue |
| Southwest SWA485 | 11:31a | 2h21m | Thu |
| American ENY3546 | 11:46a | 2h29m | Mon |
| Southwest SWA3657 | 11:52a | 2h16m | Sat |
| American ENY3546 | 12:56p | 2h23m | Sun |
| Southwest SWA2144 | 1:33p | 2h20m | Wed |
| Southwest SWA3808 | 1:45p | 2h15m | Fri |
| Southwest SWA2144 | 1:50p | 2h30m | Tue |
| Republic Airways RPA4727 | 2:43p | 2h23m | Sat |
| Southwest SWA3808 | 2:49p | 2h31m | Mon |
| Southwest SWA982 | 5:04p | 2h36m | Sat |
| Republic Airways RPA4727 | 6:15p | 2h9m | Fri |
| Republic Airways RPA4727 | 7:08p | 2h5m | Wed |
| Southwest SWA982 | 7:12p | 2h4m | Wed |
| Southwest SWA982 | 7:30p | 2h44m | Tue |
| Southwest SWA1643 | 8:03p | 2h27m | Fri |
| Republic Airways RPA4727 | 8:03p | 2h9m | Thu |
| Republic Airways RPA4727 | 8:20p | 2h9m | Tue |
| Southwest SWA1643 | 8:29p | 2h22m | Thu |
| Southwest SWA982 | 8:57p | 2h21m | Sun |
| Southwest SWA1643 | 9:20p | 2h30m | Mon |
| Republic Airways RPA4727 | 10:19p | 2h22m | Sun |
American
SouthwestThe route
One hop: STL → BOSDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from St. Louis (STL) to Boston (BOS)
St. Louis Lambert International Airport (STL) has 32 nonstop flights a week to Boston (BOS), operated by American and Southwest. No layovers, no connections — one hop out of STL and you're there.
This route flies every day of the week, so any travel day works. Route data updated October 2026 from observed departures.
Route data updated October 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from St. Louis to Boston?
The nonstop flight from St. Louis (STL) to Boston (BOS) takes about 2h22m in the air, based on recently observed nonstop departures.
How long does it take to drive from St. Louis to Boston?
Driving from St. Louis to Boston takes about 17h 39m behind the wheel — roughly 1,190 miles, or about 2 days of real driving. The nonstop flight takes about 2h22m.