Direct flights from St. Louis to Chicago
34 nonstop flights a week on 1 airline. Zero layovers — one hop from STL to MDW.
Flight time: about 44m nonstop
Which days does it fly?
When does it fly?
Departure times in St. Louis local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Southwest SWA2888 | 5:40a | 48m | Thu |
| Southwest SWA3861 | 5:56a | 42m | Sat |
| Southwest SWA4752 | 6:00a | 41m | Sun |
| Southwest SWA2052 | 6:12a | 45m | Mon |
| Southwest SWA2052 | 6:15a | 41m | Fri |
| Southwest SWA3861 | 6:42a | 52m | Tue–Wed |
| Southwest SWA3862 | 8:34a | 51m | Sat |
| Southwest SWA2814 | 9:15a | 49m | Sun |
| Southwest SWA3862 | 10:51a | 53m | Tue |
| Southwest SWA3862 | 10:57a | 42m | Wed |
| Southwest SWA4143 | 11:19a | 51m | Thu |
| Southwest SWA3861 | 11:21a | 42m | Fri |
| Southwest SWA3861 | 11:35a | 44m | Mon |
| Southwest SWA2052 | 12:52p | 42m | Tue |
| Southwest SWA2052 | 12:55p | 46m | Wed |
| Southwest SWA2052 | 1:14p | 43m | Sun |
| Southwest SWA3862 | 2:37p | 54m | Mon |
| Southwest SWA2052 | 3:12p | 44m | Sat |
| Southwest SWA3862 | 3:14p | 55m | Fri |
| Southwest SWA3862 | 3:20p | 41m | Thu |
| Southwest SWA2742 | 3:36p | 51m | Sun |
| Southwest SWA3864 | 3:54p | 42m | Tue |
| Southwest SWA3864 | 4:11p | 43m | Wed |
| Southwest SWA3001 | 6:39p | 40m | Thu |
| Southwest SWA3001 | 6:54p | 50m | Fri |
| Southwest SWA3001 | 7:31p | 50m | Mon |
| Southwest SWA2032 | 8:46p | 55m | Sun |
| Southwest SWA3865 | 8:52p | 48m | Wed, Fri |
| Southwest SWA3865 | 8:58p | 42m | Mon–Tue |
| Southwest SWA8631 | 9:26p | 42m | Wed |
| Southwest SWA3865 | 10:23p | 40m | Thu |
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The route
One hop: STL → MDWDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from St. Louis (STL) to Chicago (MDW)
St. Louis Lambert International Airport (STL) has 34 nonstop flights a week to Chicago (MDW), operated by Southwest. No layovers, no connections — one hop out of STL and you're there.
This route flies every day of the week, so any travel day works. Route data updated October 2026 from observed departures.
Route data updated October 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from St. Louis to Chicago?
The nonstop flight from St. Louis (STL) to Chicago (MDW) takes about 44m in the air, based on recently observed nonstop departures.
How long does it take to drive from St. Louis to Chicago?
Driving from St. Louis to Chicago takes about 4h 27m, covering roughly 297 miles. The nonstop flight takes about 44m.