Direct flights from St. Louis to San Antonio
13 nonstop flights a week on 1 airline. Zero layovers — one hop from STL to SAT.
Flight time: about 1h50m nonstop
Which days does it fly?
When does it fly?
Departure times in St. Louis local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Southwest SWA4166 | 7:46a | 1h54m | Sun |
| Southwest SWA4922 | 8:40a | 1h51m | Thu |
| Southwest SWA1809 | 8:40a | 1h50m | Mon, Fri |
| Southwest SWA4498 | 8:54a | 1h44m | Wed |
| Southwest SWA4498 | 8:57a | 1h49m | Tue |
| Southwest SWA4010 | 2:56p | 1h54m | Sat |
| Southwest SWA4166 | 9:00p | 1h48m | Mon, Wed, Fri |
| Southwest SWA4166 | 9:06p | 1h50m | Tue, Thu |
| Southwest SWA4390 | 11:43p | 1h52m | Sun |
Southwest
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The route
One hop: STL → SATDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from St. Louis (STL) to San Antonio (SAT)
St. Louis Lambert International Airport (STL) has 13 nonstop flights a week to San Antonio (SAT), operated by Southwest. No layovers, no connections — one hop out of STL and you're there.
This route flies every day of the week, so any travel day works. Route data updated October 2026 from observed departures.
Route data updated October 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from St. Louis to San Antonio?
The nonstop flight from St. Louis (STL) to San Antonio (SAT) takes about 1h50m in the air, based on recently observed nonstop departures.
How long does it take to drive from St. Louis to San Antonio?
Driving from St. Louis to San Antonio takes about 13h 51m, covering roughly 903 miles. The nonstop flight takes about 1h50m.