Direct flights from St. Louis to San Diego
7 nonstop flights a week on 1 airline. Zero layovers — one hop from STL to SAN.
Flight time: about 3h27m nonstop
Which days does it fly?
When does it fly?
Departure times in St. Louis local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Southwest SWA3886 | 8:36a | 3h31m | Tue, Wed, Sun |
| Southwest SWA3886 | 8:47a | 3h30m | Mon, Fri |
| Southwest SWA4403 | 8:53a | 3h22m | Thu |
| Southwest SWA3181 | 2:32p | 3h24m | Sat |
Southwest
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The route
One hop: STL → SANDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from St. Louis (STL) to San Diego (SAN)
St. Louis Lambert International Airport (STL) has 7 nonstop flights a week to San Diego (SAN), operated by Southwest. No layovers, no connections — one hop out of STL and you're there.
This route flies every day of the week, so any travel day works. Route data updated October 2026 from observed departures.
Route data updated October 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from St. Louis to San Diego?
The nonstop flight from St. Louis (STL) to San Diego (SAN) takes about 3h27m in the air, based on recently observed nonstop departures.