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McGhee Tyson Airport · TYS

Direct flights from Knoxville

40 nonstop destinations. Zero layovers, zero connections — just one hop out of TYS.

40
Nonstop cities
9
Airlines
485
Flights / week
TYS
Your origin

Where one hop gets you

Dashed arcs = nonstop routes from TYS · updates with the day filter
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What changed in the past year

Comparing August 2025 with September 2026 · TYS

  • American stopped flying to Atlanta.
  • Frontier stopped flying to Denver.
  • Allegiant stopped flying to Minneapolis.
  • Nonstop service to Nashville began, now 15 flights a week.
  • Nonstop service to Baltimore began, now 7 flights a week.
  • Nonstop service to Dallas began, now 7 flights a week.
  • Southwest started flying to Denver.
  • Southwest started flying to Orlando (MCO).

…and 14 smaller changes over the same period.

TYS also serves
Before you go

Parking rates & lots at McGhee Tyson Airport official airport site · flyknoxville.com

Where can you fly nonstop from Knoxville (TYS)?

McGhee Tyson Airport (TYS) offers nonstop flights to 40 destinations across the United States. The busiest direct routes from TYS are served by American, United, Delta and Allegiant, with the most frequent nonstop service to Atlanta, Chicago and Charlotte.

Every route below leaves TYS and lands at your destination — no layovers, no connections. Use the day filter above to see exactly which routes fly on the day you want to travel. Route data updated September 2026 from observed departures.

Airlines and flight times at TYS

9 airlines fly nonstop out of TYS. American runs the biggest operation — about 174 of the 446 weekly departures (39%), across 7 routes — followed by Delta and United.

The airlines flying nonstop out of Knoxville are American, Delta, United, Allegiant, Southwest, Frontier, Avelo Airlines, Contour Airlines and Sun Country.

On 31 of Knoxville's 40 nonstop routes, a single airline has the service to itself — American is the only airline with a nonstop to Charlotte, and United the only one to Washington (IAD).

The shortest nonstop out of TYS is Atlanta at about 36m in the air; the longest is Las Vegas at about 4h6m.

Route data updated September 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.