Direct flights from Knoxville to Chicago
2 nonstop flights a week on 1 airline. Zero layovers — one hop from TYS to MDW.
Flight time: about 1h23m nonstop
Which days does it fly?
When does it fly?
Departure times in Knoxville local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Allegiant AAY3023 | 1:25p | 1h16m | Sun |
| Allegiant AAY3037 | 1:26p | 1h29m | Thu |
Allegiant
Find fares 🥕
The route
One hop: TYS → MDWDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Knoxville (TYS) to Chicago (MDW)
McGhee Tyson Airport (TYS) has 2 nonstop flights a week to Chicago (MDW), operated by Allegiant. No layovers, no connections — one hop out of TYS and you're there.
This route flies on Thursday and Sunday — check the schedule grid above before you pick a travel day. Route data updated July 2026 from observed departures.
Route data updated July 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Knoxville to Chicago?
The nonstop flight from Knoxville (TYS) to Chicago (MDW) takes about 1h23m in the air, based on recently observed nonstop departures.
How long does it take to drive from Knoxville to Chicago?
Driving from Knoxville to Chicago takes about 8h 9m, covering roughly 541 miles. The nonstop flight takes about 1h23m.