Direct flights from Knoxville to Charlotte
51 nonstop flights a week on 2 airlines. Zero layovers — one hop from TYS to CLT.
Flight time: about 42m nonstop
Which days does it fly?
When does it fly?
Departure times in Knoxville local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| American PDT5954 | 5:04a | 48m | Fri |
| American PDT5954 | 5:08a | 44m | Mon, Tue, Sat, Sun |
| American PDT5954 | 5:17a | 29m | Thu |
| American PDT5954 | 6:15a | 48m | Wed |
| American PDT5947 | 9:04a | 42m | Sat–Sun |
| American PDT5947 | 9:11a | 56m | Mon, Thu, Fri |
| American JIA5182 | 10:08a | 34m | Mon, Thu, Fri, Sat |
| American JIA5182 | 10:45a | 21m | Wed |
| American PDT5950 | 11:12a | 46m | Mon, Thu, Fri, Sun |
| American PDT5950 | 11:18a | 46m | Tue, Sat |
| American JIA5182 | 11:39a | 39m | Tue |
| American PDT5950 | 11:53a | 46m | Wed |
| American JIA5182 | 12:00p | 22m | Sun |
| American JIA9950 | 12:17p | 28m | Fri |
| American PDT5953 | 1:08p | 47m | Mon–Tue |
| American PDT5953 | 1:18p | 47m | Thu |
| American JIA5182 | 3:22p | 32m | Tue |
| American PDT5831 | 4:20p | 38m | Mon–Tue |
| American PDT5953 | 4:23p | 45m | Wed |
| American PDT5831 | 4:28p | 36m | Wed–Thu |
| American PDT5831 | 4:48p | 38m | Sat–Sun |
| American PDT5831 | 4:59p | 45m | Fri |
| SkyWest SKW6439 | 6:17p | 41m | Thu |
| American JIA5598 | 6:21p | 38m | Tue |
| SkyWest SKW6439 | 6:26p | 26m | Fri |
| American JIA5598 | 6:54p | 28m | Wed |
| SkyWest SKW6439 | 7:02p | 40m | Mon |
| American PDT5957 | 8:09p | 44m | Wed |
| American PDT5957 | 8:21p | 44m | Mon |
| American PDT5957 | 8:27p | 44m | Thu |
| SkyWest SKW6439 | 8:28p | 40m | Sun |
| American PDT5957 | 8:45p | 44m | Fri |
| American PDT5957 | 9:00p | 44m | Sat–Sun |
AmericanThe route
One hop: TYS → CLTDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Knoxville (TYS) to Charlotte (CLT)
McGhee Tyson Airport (TYS) has 51 nonstop flights a week to Charlotte (CLT), operated by American and SkyWest. No layovers, no connections — one hop out of TYS and you're there.
This route flies every day of the week, so any travel day works. Route data updated July 2026 from observed departures.
Route data updated July 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Knoxville to Charlotte?
The nonstop flight from Knoxville (TYS) to Charlotte (CLT) takes about 42m in the air, based on recently observed nonstop departures.
How long does it take to drive from Knoxville to Charlotte?
Driving from Knoxville to Charlotte takes about 3h 55m — roughly 230 miles — so the car is a real alternative on this route. The nonstop flight takes about 42m.