Direct flights from Knoxville to Minneapolis
13 nonstop flights a week on 1 airline. Zero layovers — one hop from TYS to MSP.
Flight time: about 2h4m nonstop
Which days does it fly?
When does it fly?
Departure times in Knoxville local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Delta EDV5523 | 6:33a | 1h56m | Tue, Thu, Sat |
| Delta EDV5523 | 6:39a | 2h5m | Mon, Wed, Fri |
| Delta EDV5523 | 7:05a | 2h9m | Sun |
| Delta EDV4803 | 6:19p | 1h52m | Tue |
| Delta EDV4803 | 6:27p | 2h3m | Wed–Thu |
| Delta EDV4803 | 6:35p | 2h4m | Mon |
| Delta EDV4803 | 6:53p | 1h30m | Fri |
| Delta EDV4803 | 8:00p | 2h10m | Sun |
Delta
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The route
One hop: TYS → MSPDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Knoxville (TYS) to Minneapolis (MSP)
McGhee Tyson Airport (TYS) has 13 nonstop flights a week to Minneapolis (MSP), operated by Delta. No layovers, no connections — one hop out of TYS and you're there.
This route flies every day of the week, so any travel day works. Route data updated September 2026 from observed departures.
Route data updated September 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Knoxville to Minneapolis?
The nonstop flight from Knoxville (TYS) to Minneapolis (MSP) takes about 2h4m in the air, based on recently observed nonstop departures.
How long does it take to drive from Knoxville to Minneapolis?
Driving from Knoxville to Minneapolis takes about 13h 57m, covering roughly 948 miles. The nonstop flight takes about 2h4m.