Direct flights from Knoxville to Minneapolis
14 nonstop flights a week on 2 airlines. Zero layovers — one hop from TYS to MSP.
Flight time: about 2h nonstop
Which days does it fly?
When does it fly?
Departure times in Knoxville local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Delta EDV5523 | 6:44a | 1h52m | Fri |
| Delta EDV5523 | 6:53a | 2h6m | Mon, Wed, Sat, Sun |
| Delta EDV5523 | 6:58a | 1h39m | Thu |
| Delta EDV5523 | 7:40a | 2h6m | Tue |
| American JIA9965 | 12:33p | 1h54m | Tue |
| Delta EDV4803 | 6:53p | 1h51m | Fri |
| Delta EDV4803 | 7:02p | 2h7m | Wed |
| Delta EDV4803 | 7:12p | 2h | Sun |
| Delta EDV4803 | 7:16p | 1h55m | Thu |
| Delta EDV4803 | 7:35p | 2h11m | Mon |
| Delta EDV4803 | 8:21p | 2h21m | Tue |
Delta
AmericanThe route
One hop: TYS → MSPDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Knoxville (TYS) to Minneapolis (MSP)
McGhee Tyson Airport (TYS) has 14 nonstop flights a week to Minneapolis (MSP), operated by Delta and American. No layovers, no connections — one hop out of TYS and you're there.
This route flies every day of the week, so any travel day works. Route data updated July 2026 from observed departures.
Route data updated July 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Knoxville to Minneapolis?
The nonstop flight from Knoxville (TYS) to Minneapolis (MSP) takes about 2h in the air, based on recently observed nonstop departures.
How long does it take to drive from Knoxville to Minneapolis?
Driving from Knoxville to Minneapolis takes about 13h 57m, covering roughly 948 miles. The nonstop flight takes about 2h.