Home › Des Moines (DSM) › American
American · Des Moines International Airport · DSM

American nonstop flights from Des Moines

9 nonstop destinations on American out of DSM — 35% of everything that departs. Zero layovers, zero connections.

9
Nonstop cities
35%
of DSM departures
126
Flights / week
DSM
Your origin

Where American can take you

Dashed arcs = American nonstop routes from DSM · updates with the day filter
Filter by day you want to fly
Looking wider?

All nonstop destinations from Des Moines (DSM) every airline, not just American

Everywhere American flies 346 airports

American flight numbers from Des Moines (DSM)

Each one's timetable, usual aircraft and how it ran in our sample.

AA2326 to Dallas-Fort Worth AA1985 to Charlotte AA1428 to Phoenix AA1318 to Phoenix AA1680 to Dallas-Fort Worth AA1763 to Charlotte AA3191 to Dallas-Fort Worth All 2,053 American flight numbers →

Where can you fly nonstop on American from Des Moines (DSM)?

American flies 9 nonstop routes from Des Moines International Airport (DSM), around 126 departures a week — 35% of everything leaving DSM.

Its busiest is Des Moines to Chicago at 28 American flights a week. 5 of these 9 destinations have no other nonstop operator from DSM, so American is the only way to reach them without a connection.

Use the day filter above to see which American routes fly on the day you want to travel. Route data updated November 2026 from observed departures.

Frequencies shown are American's own departures, counted from observed schedules. Schedules change — always confirm with the airline before booking.