Direct flights from Knoxville to Harrisburg
1 nonstop flight a week on 1 airline. Zero layovers — one hop from TYS to MDT.
Flight time: about 1h4m nonstop
Which days does it fly?
When does it fly?
Departure times in Knoxville local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| American PDT9988 | 7:09p | 1h4m | Sat |
American
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The route
One hop: TYS → MDTDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Knoxville (TYS) to Harrisburg (MDT)
McGhee Tyson Airport (TYS) has 1 nonstop flight a week to Harrisburg (MDT), operated by American. No layovers, no connections — one hop out of TYS and you're there.
This route flies on Saturday — check the schedule grid above before you pick a travel day. Route data updated July 2026 from observed departures.
Route data updated July 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Knoxville to Harrisburg?
The nonstop flight from Knoxville (TYS) to Harrisburg (MDT) takes about 1h4m in the air, based on recently observed nonstop departures.
How long does it take to drive from Knoxville to Harrisburg?
Driving from Knoxville to Harrisburg takes about 8h 4m, covering roughly 541 miles. The nonstop flight takes about 1h4m.