Direct flights from Knoxville to Charleston

1 nonstop flight a week on 1 airline. Zero layovers — one hop from TYS to CRW.

Which days does it fly?

American Find fares 🥕

The route

One hop: TYS → CRW

Nonstop from Knoxville (TYS) to Charleston (CRW)

McGhee Tyson Airport (TYS) has 1 nonstop flight a week to Charleston (CRW), operated by American. No layovers, no connections — one hop out of TYS and you're there.

This route flies on Tuesday — check the schedule grid above before you pick a travel day. Route data updated September 2026 from observed departures.

Route data updated September 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.

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