Direct flights from Knoxville to Buffalo
1 nonstop flight a week on 1 airline. Zero layovers — one hop from TYS to BUF.
Flight time: about 1h13m nonstop
Which days does it fly?
When does it fly?
Departure times in Knoxville local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Delta EDV5558 | 6:54p | 1h13m | Sat |
Delta
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The route
One hop: TYS → BUFDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Knoxville (TYS) to Buffalo (BUF)
McGhee Tyson Airport (TYS) has 1 nonstop flight a week to Buffalo (BUF), operated by Delta. No layovers, no connections — one hop out of TYS and you're there.
This route flies on Saturday — check the schedule grid above before you pick a travel day. Route data updated August 2026 from observed departures.
Route data updated August 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Knoxville to Buffalo?
The nonstop flight from Knoxville (TYS) to Buffalo (BUF) takes about 1h13m in the air, based on recently observed nonstop departures.