American nonstop flights from Greenville
10 nonstop destinations on American out of GSP — 43% of everything that departs. Zero layovers, zero connections.
Where American can take you
Dashed arcs = American nonstop routes from GSP · updates with the day filterDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
All nonstop destinations from Greenville (GSP) every airline, not just American
Everywhere American flies 346 airports
AmericanAmerican flight numbers from Greenville (GSP)
Each one's timetable, usual aircraft and how it ran in our sample.
Where can you fly nonstop on American from Greenville (GSP)?
American flies 10 nonstop routes from Greenville-Spartanburg International Airport (GSP), around 179 departures a week — 43% of everything leaving GSP.
Its busiest is Greenville to Charlotte at 59 American flights a week. 7 of these 10 destinations have no other nonstop operator from GSP, so American is the only way to reach them without a connection.
Use the day filter above to see which American routes fly on the day you want to travel. Route data updated November 2026 from observed departures.
Frequencies shown are American's own departures, counted from observed schedules. Schedules change — always confirm with the airline before booking.