Direct flights from Greenville to Chicago
41 nonstop flights a week on 2 airlines. Zero layovers — one hop from GSP to ORD.
Flight time: about 1h25m nonstop
Which days does it fly?
When does it fly?
Departure times in Greenville local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| SkyWest SKW4728 | 6:21a | 1h18m | Wed, Fri, Sun |
| SkyWest SKW4728 | 6:28a | 1h18m | Mon, Thu, Sat |
| SkyWest SKW4728 | 7:03a | 1h18m | Tue |
| American ENY3564 | 7:47a | 1h30m | Sat |
| American ENY3564 | 8:24a | 1h34m | Thu |
| American ENY3564 | 8:28a | 1h28m | Tue–Wed |
| American ENY3564 | 9:00a | 1h26m | Mon |
| American ENY3564 | 9:31a | 1h48m | Fri, Sun |
| SkyWest SKW5361 | 10:50a | 1h20m | Mon, Fri |
| SkyWest SKW5361 | 11:01a | 1h29m | Thu |
| SkyWest SKW5361 | 11:09a | 1h18m | Wed, Sat |
| American ENY3556 | 11:40a | 1h25m | Thu, Fri, Sun |
| American ENY3556 | 11:47a | 1h28m | Mon–Wed |
| SkyWest SKW5361 | 12:03p | 1h23m | Tue |
| SkyWest SKW5361 | 12:11p | 1h18m | Sun |
| American ENY3556 | 12:13p | 1h48m | Sat |
| SkyWest SKW5524 | 5:50p | 1h30m | Mon, Sun |
| SkyWest SKW5524 | 6:01p | 1h18m | Tue–Thu |
| SkyWest SKW5524 | 6:09p | 1h18m | Sat |
| American ENY3559 | 6:54p | 1h25m | Sun |
| American ENY3559 | 7:30p | 1h29m | Wed |
| American ENY3559 | 7:35p | 1h26m | Tue |
| SkyWest SKW5524 | 7:50p | 1h18m | Fri |
| American ENY3559 | 7:52p | 1h23m | Mon |
| American ENY3559 | 8:21p | 1h24m | Thu |
| American ENY3559 | 8:40p | 1h29m | Fri |
AmericanThe route
One hop: GSP → ORDDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Greenville (GSP) to Chicago (ORD)
Greenville-Spartanburg International Airport (GSP) has 41 nonstop flights a week to Chicago (ORD), operated by American and SkyWest. No layovers, no connections — one hop out of GSP and you're there.
This route flies every day of the week, so any travel day works. Route data updated July 2026 from observed departures.
Route data updated July 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Greenville to Chicago?
The nonstop flight from Greenville (GSP) to Chicago (ORD) takes about 1h25m in the air, based on recently observed nonstop departures.
How long does it take to drive from Greenville to Chicago?
Driving from Greenville to Chicago takes about 11h 3m, covering roughly 708 miles. The nonstop flight takes about 1h25m.