Direct flights from Boston to St Louis
34 nonstop flights a week on 3 airlines. Zero layovers — one hop from BOS to STL.
Flight time: about 2h22m nonstop
Which days does it fly?
When does it fly?
Departure times in Boston local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Southwest SWA752 | 5:37a | 2h24m | Thu–Fri |
| Southwest SWA752 | 5:50a | 2h18m | Mon |
| Southwest SWA752 | 5:56a | 2h18m | Wed, Sat, Sun |
| Southwest SWA752 | 6:08a | 2h13m | Tue |
| Republic Airways RPA4582 | 7:08a | 2h7m | Sun |
| American ENY3814 | 7:10a | 2h13m | Mon–Tue |
| American ENY3814 | 7:29a | 2h28m | Fri |
| American ENY3814 | 7:36a | 2h27m | Thu |
| American ENY3814 | 8:27a | 2h20m | Wed |
| Southwest SWA766 | 10:17a | 2h29m | Sat |
| Southwest SWA4917 | 1:04p | 2h21m | Fri |
| Southwest SWA4917 | 1:07p | 2h22m | Tue–Thu |
| Southwest SWA4917 | 1:16p | 2h19m | Mon |
| Republic Airways RPA4678 | 2:10p | 2h26m | Sat |
| Southwest SWA4917 | 2:36p | 2h27m | Sat |
| Southwest SWA4917 | 2:52p | 2h23m | Sun |
| Republic Airways RPA4678 | 5:24p | 2h11m | Tue |
| Republic Airways RPA4678 | 5:31p | 2h28m | Wed |
| Republic Airways RPA4678 | 5:35p | 2h21m | Mon, Thu, Sun |
| Republic Airways RPA4678 | 5:48p | 2h4m | Fri |
| Southwest SWA754 | 6:58p | 2h21m | Wed |
| Southwest SWA754 | 7:12p | 2h22m | Tue |
| Southwest SWA754 | 7:20p | 2h25m | Sun |
| Southwest SWA754 | 7:38p | 2h24m | Mon, Thu, Fri |
American
SouthwestThe route
One hop: BOS → STLDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Boston (BOS) to St Louis (STL)
Boston Logan International Airport (BOS) has 34 nonstop flights a week to St Louis (STL), operated by American, Republic Airways and Southwest. No layovers, no connections — one hop out of BOS and you're there.
This route flies every day of the week, so any travel day works. Route data updated July 2026 from observed departures.
Route data updated July 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Boston to St Louis?
The nonstop flight from Boston (BOS) to St Louis (STL) takes about 2h22m in the air, based on recently observed nonstop departures.
How long does it take to drive from Boston to St Louis?
Driving from Boston to St Louis takes about 17h 39m behind the wheel — roughly 1,190 miles, or about 2 days of real driving. The nonstop flight takes about 2h22m.