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American · Roanoke–Blacksburg Regional Airport · ROA

American nonstop flights from Roanoke

5 nonstop destinations on American out of ROA — 51% of everything that departs. Zero layovers, zero connections.

5
Nonstop cities
51%
of ROA departures
91
Flights / week
ROA
Your origin

Where American can take you

Dashed arcs = American nonstop routes from ROA · updates with the day filter
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All nonstop destinations from Roanoke (ROA) every airline, not just American

Everywhere American flies 346 airports

Where can you fly nonstop on American from Roanoke (ROA)?

American flies 5 nonstop routes from Roanoke–Blacksburg Regional Airport (ROA), around 91 departures a week — 51% of everything leaving ROA.

Its busiest is Roanoke to Charlotte at 57 American flights a week. 2 of these 5 destinations have no other nonstop operator from ROA, so American is the only way to reach them without a connection.

Use the day filter above to see which American routes fly on the day you want to travel. Route data updated November 2026 from observed departures.

Frequencies shown are American's own departures, counted from observed schedules. Schedules change — always confirm with the airline before booking.