Direct flights from Milwaukee to St Louis
13 nonstop flights a week on 1 airline. Zero layovers — one hop from MKE to STL.
Flight time: about 50m nonstop
Which days does it fly?
When does it fly?
Departure times in Milwaukee local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Southwest SWA3213 | 6:29a | 51m | Sat |
| Southwest SWA2327 | 7:20a | 50m | Mon, Thu |
| Southwest SWA2327 | 8:09a | 51m | Wed, Fri, Sun |
| Southwest SWA2327 | 8:15a | 52m | Tue |
| Southwest SWA1014 | 5:05p | 49m | Wed |
| Southwest SWA3599 | 5:17p | 47m | Sat |
| Southwest SWA4661 | 5:58p | 52m | Fri |
| Southwest SWA1014 | 6:06p | 46m | Tue |
| Southwest SWA4661 | 6:23p | 50m | Thu |
| Southwest SWA4661 | 6:38p | 48m | Mon |
SouthwestThe route
One hop: MKE → STLDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Milwaukee (MKE) to St Louis (STL)
General Mitchell International Airport (MKE) has 13 nonstop flights a week to St Louis (STL), operated by Southwest. No layovers, no connections — one hop out of MKE and you're there.
This route flies every day of the week, so any travel day works. Route data updated August 2026 from observed departures.
Route data updated August 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Milwaukee to St Louis?
The nonstop flight from Milwaukee (MKE) to St Louis (STL) takes about 50m in the air, based on recently observed nonstop departures.
How long does it take to drive from Milwaukee to St Louis?
Driving from Milwaukee to St Louis takes about 5h 31m, covering roughly 373 miles. The nonstop flight takes about 50m.