Direct flights from Columbus to St Louis
13 nonstop flights a week on 1 airline. Zero layovers — one hop from CMH to STL.
Flight time: about 1h5m nonstop
Which days does it fly?
When does it fly?
Departure times in Columbus local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Southwest SWA4572 | 6:45a | 1h1m | Sun |
| Southwest SWA4203 | 7:08a | 1h6m | Tue–Wed |
| Southwest SWA4203 | 7:25a | 1h3m | Sat |
| Southwest SWA1785 | 7:29a | 1h10m | Mon, Thu, Fri |
| Southwest SWA1656 | 7:24p | 1h | Wed |
| Southwest SWA4203 | 7:41p | 1h10m | Fri |
| Southwest SWA4203 | 8:01p | 1h2m | Mon |
| Southwest SWA1656 | 8:03p | 1h1m | Tue |
| Southwest SWA4203 | 8:31p | 1h17m | Sun |
| Southwest SWA4203 | 8:38p | 1h14m | Thu |
SouthwestThe route
One hop: CMH → STLDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Columbus (CMH) to St Louis (STL)
John Glenn Columbus International Airport (CMH) has 13 nonstop flights a week to St Louis (STL), operated by Southwest. No layovers, no connections — one hop out of CMH and you're there.
This route flies every day of the week, so any travel day works. Route data updated September 2026 from observed departures.
Route data updated September 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Columbus to St Louis?
The nonstop flight from Columbus (CMH) to St Louis (STL) takes about 1h5m in the air, based on recently observed nonstop departures.
How long does it take to drive from Columbus to St Louis?
Driving from Columbus to St Louis takes about 6h 18m, covering roughly 417 miles. The nonstop flight takes about 1h5m.