Direct flights from Cleveland to St Louis
13 nonstop flights a week on 1 airline. Zero layovers — one hop from CLE to STL.
Flight time: about 1h7m nonstop
Which days does it fly?
When does it fly?
Departure times in Cleveland local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Southwest SWA1165 | 6:30a | 1h8m | Mon, Fri |
| Southwest SWA1165 | 6:36a | 1h9m | Thu |
| Southwest SWA1165 | 7:12a | 1h9m | Tue, Wed, Sat |
| Southwest SWA1165 | 7:23a | 1h6m | Sun |
| Southwest SWA2864 | 7:37p | 1h6m | Sun |
| Southwest SWA792 | 7:57p | 1h5m | Tue |
| Southwest SWA792 | 8:35p | 1h5m | Wed |
| Southwest SWA747 | 8:53p | 1h4m | Mon |
| Southwest SWA747 | 8:57p | 1h9m | Thu |
| Southwest SWA747 | 9:05p | 1h11m | Fri |
Southwest
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The route
One hop: CLE → STLDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Cleveland (CLE) to St Louis (STL)
Cleveland Hopkins International Airport (CLE) has 13 nonstop flights a week to St Louis (STL), operated by Southwest. No layovers, no connections — one hop out of CLE and you're there.
This route flies every day of the week, so any travel day works. Route data updated July 2026 from observed departures.
Route data updated July 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Cleveland to St Louis?
The nonstop flight from Cleveland (CLE) to St Louis (STL) takes about 1h7m in the air, based on recently observed nonstop departures.
How long does it take to drive from Cleveland to St Louis?
Driving from Cleveland to St Louis takes about 8h 20m, covering roughly 557 miles. The nonstop flight takes about 1h7m.