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American nonstop flights from Charleston

7 nonstop destinations on American out of CHS — 29% of everything that departs. Zero layovers, zero connections.

7
Nonstop cities
29%
of CHS departures
179
Flights / week
CHS
Your origin

Where American can take you

Dashed arcs = American nonstop routes from CHS · updates with the day filter
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All nonstop destinations from Charleston (CHS) every airline, not just American

Everywhere American flies 346 airports

American flight numbers from Charleston (CHS)

Each one's timetable, usual aircraft and how it ran in our sample — 12 of the 15 we cover from CHS, flown most days first.

Where can you fly nonstop on American from Charleston (CHS)?

American flies 7 nonstop routes from Charleston International Airport (CHS), around 179 departures a week — 29% of everything leaving CHS.

Its busiest is Charleston to Charlotte at 50 American flights a week. 4 of these 7 destinations have no other nonstop operator from CHS, so American is the only way to reach them without a connection.

Use the day filter above to see which American routes fly on the day you want to travel. Route data updated November 2026 from observed departures.

Frequencies shown are American's own departures, counted from observed schedules. Schedules change — always confirm with the airline before booking.