Direct flights from Sioux Falls

Where can you fly nonstop from Sioux Falls (FSD)?

Sioux Falls Regional Airport (FSD) offers nonstop flights to 21 destinations across the United States. The busiest direct routes from FSD are served by United, American, Frontier and Delta, with the most frequent nonstop service to Chicago, Denver and Minneapolis.

Every route below leaves FSD and lands at your destination — no layovers, no connections. Use the day filter above to see exactly which routes fly on the day you want to travel. Route data updated October 2026 from observed departures.

Airlines and flight times at FSD

6 airlines fly nonstop out of FSD. Delta runs the biggest operation — about 41 of the 110 weekly departures (37%), across 2 routes — followed by American and Allegiant.

The airlines flying nonstop out of Sioux Falls are Delta, American, Allegiant, United, Frontier and JetBlue.

On 17 of Sioux Falls's 21 nonstop routes, a single airline has the service to itself — Delta is the only airline with a nonstop to Minneapolis, and American the only one to Dallas-Fort Worth.

The shortest nonstop out of FSD is Minneapolis at about 31m in the air; the longest is Medford at about 3h1m.

Route data updated October 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.