Direct flights from Rochester to Knoxville
1 nonstop flight a week on 1 airline. Zero layovers — one hop from ROC to TYS.
Flight time: about 1h32m nonstop
Which days does it fly?
When does it fly?
Departure times in Rochester local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| American JIA5377 | 4:38p | 1h32m | Tue |
American
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The route
One hop: ROC → TYSDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Rochester (ROC) to Knoxville (TYS)
Frederick Douglass Greater Rochester International Airport (ROC) has 1 nonstop flight a week to Knoxville (TYS), operated by American. No layovers, no connections — one hop out of ROC and you're there.
This route flies on Tuesday — check the schedule grid above before you pick a travel day. Route data updated August 2026 from observed departures.
Route data updated August 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Rochester to Knoxville?
The nonstop flight from Rochester (ROC) to Knoxville (TYS) takes about 1h32m in the air, based on recently observed nonstop departures.
How long does it take to drive from Rochester to Knoxville?
Driving from Rochester to Knoxville takes about 11h 5m, covering roughly 752 miles. The nonstop flight takes about 1h32m.