Direct flights from Louisville to San Francisco
2 nonstop flights a week on 1 airline. Zero layovers — one hop from SDF to SFO.
Flight time: about 4h44m nonstop
Which days does it fly?
When does it fly?
Departure times in Louisville local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Breeze Airways MXY228 | 8:54a | 4h44m | Mon |
| Breeze Airways MXY228 | 8:56a | 4h44m | Fri |
The route
One hop: SDF → SFODrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Louisville (SDF) to San Francisco (SFO)
Louisville Muhammad Ali International Airport (SDF) has 2 nonstop flights a week to San Francisco (SFO), operated by Breeze Airways. No layovers, no connections — one hop out of SDF and you're there.
This route flies on Monday and Friday — check the schedule grid above before you pick a travel day. Route data updated September 2026 from observed departures.
Route data updated September 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Louisville to San Francisco?
The nonstop flight from Louisville (SDF) to San Francisco (SFO) takes about 4h44m in the air, based on recently observed nonstop departures.
How long does it take to drive from Louisville to San Francisco?
Driving from Louisville to San Francisco takes about 34h 3m behind the wheel — roughly 2,312 miles, or about 3 days of real driving. The nonstop flight takes about 4h44m.