Direct flights from Louisville to Roanoke

1 nonstop flight a week on 1 airline. Zero layovers — one hop from SDF to ROA.

Which days does it fly?

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The route

One hop: SDF → ROA

Nonstop from Louisville (SDF) to Roanoke (ROA)

Louisville Muhammad Ali International Airport (SDF) has 1 nonstop flight a week to Roanoke (ROA), operated by Delta. No layovers, no connections — one hop out of SDF and you're there.

This route flies on Thursday — check the schedule grid above before you pick a travel day. Route data updated September 2026 from observed departures.

Route data updated September 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.

How long does it take to drive from Louisville to Roanoke?

Driving from Louisville to Roanoke takes about 6h 42m, covering roughly 427 miles.

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