Direct flights from Louisville to Chicago
21 nonstop flights a week on 1 airline. Zero layovers — one hop from SDF to MDW.
Flight time: about 57m nonstop
Which days does it fly?
When does it fly?
Departure times in Louisville local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Southwest SWA3522 | 8:44a | 52m | Sun |
| Southwest SWA3522 | 8:52a | 58m | Tue |
| Southwest SWA3522 | 8:58a | 50m | Wed |
| Southwest SWA3522 | 9:14a | 1h3m | Mon, Fri, Sat |
| Southwest SWA3522 | 9:16a | 58m | Thu |
| Southwest SWA8665 | 10:20a | 57m | Sun |
| Southwest SWA3523 | 1:20p | 58m | Tue–Wed |
| Southwest SWA2386 | 2:31p | 50m | Mon, Thu, Fri |
| Southwest SWA704 | 3:05p | 58m | Sun |
| Southwest SWA4370 | 5:46p | 50m | Sat |
| Southwest SWA4503 | 6:42p | 1h | Tue |
| Southwest SWA4503 | 7:14p | 57m | Wed |
| Southwest SWA4503 | 7:32p | 54m | Thu–Fri |
| Southwest SWA3575 | 7:36p | 50m | Sun |
| Southwest SWA4503 | 7:42p | 53m | Mon |
SouthwestThe route
One hop: SDF → MDWDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Louisville (SDF) to Chicago (MDW)
Louisville Muhammad Ali International Airport (SDF) has 21 nonstop flights a week to Chicago (MDW), operated by Southwest. No layovers, no connections — one hop out of SDF and you're there.
This route flies every day of the week, so any travel day works. Route data updated September 2026 from observed departures.
Route data updated September 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Louisville to Chicago?
The nonstop flight from Louisville (SDF) to Chicago (MDW) takes about 57m in the air, based on recently observed nonstop departures.
How long does it take to drive from Louisville to Chicago?
Driving from Louisville to Chicago takes about 4h 37m, covering roughly 298 miles. The nonstop flight takes about 57m.