Direct flights from Louisville to Buffalo
1 nonstop flight a week on 1 airline. Zero layovers — one hop from SDF to BUF.
Flight time: about 1h1m nonstop
Which days does it fly?
When does it fly?
Departure times in Louisville local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Republic Airways RPA3289 | 1:07p | 1h1m | Tue |
The route
One hop: SDF → BUFDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Louisville (SDF) to Buffalo (BUF)
Louisville Muhammad Ali International Airport (SDF) has 1 nonstop flight a week to Buffalo (BUF), operated by Republic Airways. No layovers, no connections — one hop out of SDF and you're there.
This route flies on Tuesday — check the schedule grid above before you pick a travel day. Route data updated July 2026 from observed departures.
Route data updated July 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Louisville to Buffalo?
The nonstop flight from Louisville (SDF) to Buffalo (BUF) takes about 1h1m in the air, based on recently observed nonstop departures.
How long does it take to drive from Louisville to Buffalo?
Driving from Louisville to Buffalo takes about 7h 58m, covering roughly 532 miles. The nonstop flight takes about 1h1m.