Direct flights from Houston to Knoxville
21 nonstop flights a week on 1 airline. Zero layovers — one hop from IAH to TYS.
Flight time: about 1h45m nonstop
Which days does it fly?
When does it fly?
Departure times in Houston local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| United ASH6291 | 8:00a | 1h45m | Tue |
| United ASH6291 | 8:08a | 1h45m | Wed–Sun |
| United ASH6291 | 9:03a | 1h45m | Mon |
| United ASH4047 | 2:54p | 1h45m | Sun |
| United ASH4047 | 2:58p | 1h45m | Mon, Tue, Wed, Sat |
| United ASH4047 | 3:17p | 1h45m | Fri |
| United ASH4047 | 4:58p | 1h45m | Thu |
| United ASH4005 | 6:40p | 1h45m | Tue, Sat |
| United ASH4005 | 6:49p | 1h51m | Mon, Fri |
| United ASH4005 | 7:00p | 1h54m | Wed–Thu |
| United ASH4005 | 7:49p | 1h36m | Sun |
United
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The route
One hop: IAH → TYSDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Houston (IAH) to Knoxville (TYS)
George Bush Intercontinental Airport (IAH) has 21 nonstop flights a week to Knoxville (TYS), operated by United. No layovers, no connections — one hop out of IAH and you're there.
This route flies every day of the week, so any travel day works. Route data updated October 2026 from observed departures.
Route data updated October 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Houston to Knoxville?
The nonstop flight from Houston (IAH) to Knoxville (TYS) takes about 1h45m in the air, based on recently observed nonstop departures.
How long does it take to drive from Houston to Knoxville?
Driving from Houston to Knoxville takes about 13h 28m, covering roughly 926 miles. The nonstop flight takes about 1h45m.