Direct flights from Detroit to Knoxville
22 nonstop flights a week on 1 airline. Zero layovers — one hop from DTW to TYS.
Flight time: about 1h nonstop
Which days does it fly?
When does it fly?
Departure times in Detroit local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Delta EDV5347 | 8:42a | 1h | Tue, Sat |
| Delta EDV5347 | 8:51a | 1h4m | Mon, Wed, Thu, Fri, Sun |
| Delta EDV5553 | 9:39a | 56m | Sun |
| Delta EDV5347 | 10:45a | 1h2m | Fri |
| Delta EDV4989 | 4:04p | 1h | Tue |
| Delta EDV4989 | 4:13p | 1h | Wed, Thu, Sun |
| Delta EDV4989 | 4:20p | 1h | Fri |
| Delta EDV4989 | 4:33p | 1h16m | Mon |
| Delta EDV5138 | 6:06p | 55m | Sat |
| Delta EDV5138 | 8:22p | 54m | Sun |
| Delta EDV5138 | 8:27p | 1h4m | Mon–Thu |
| Delta EDV5138 | 8:50p | 1h5m | Fri |
Delta
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The route
One hop: DTW → TYSDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Detroit (DTW) to Knoxville (TYS)
Detroit Metropolitan Wayne County Airport (DTW) has 22 nonstop flights a week to Knoxville (TYS), operated by Delta. No layovers, no connections — one hop out of DTW and you're there.
This route flies every day of the week, so any travel day works. Route data updated October 2026 from observed departures.
Route data updated October 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Detroit to Knoxville?
The nonstop flight from Detroit (DTW) to Knoxville (TYS) takes about 1h in the air, based on recently observed nonstop departures.
How long does it take to drive from Detroit to Knoxville?
Driving from Detroit to Knoxville takes about 7h 32m, covering roughly 512 miles. The nonstop flight takes about 1h.