Direct flights from Denver to Knoxville
23 nonstop flights a week on 3 airlines. Zero layovers — one hop from DEN to TYS.
Flight time: about 2h24m nonstop
Which days does it fly?
When does it fly?
Departure times in Denver local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Allegiant AAY3027 | 8:58a | 2h54m | Thu |
| Allegiant AAY3027 | 9:18a | 2h15m | Sun |
| United UAL1241 | 11:03a | 2h18m | Sat |
| United UAL1241 | 11:08a | 2h22m | Wed, Fri, Sun |
| United UAL1241 | 11:22a | 2h23m | Thu |
| Southwest SWA232 | 11:26a | 2h37m | Fri |
| United UAL1241 | 11:29a | 2h17m | Mon |
| United UAL1241 | 11:38a | 2h29m | Tue |
| Southwest SWA1711 | 11:43a | 2h33m | Sat |
| Southwest SWA232 | 11:50a | 2h24m | Mon, Thu |
| Southwest SWA1711 | 11:57a | 2h36m | Wed |
| Southwest SWA1711 | 12:09p | 2h22m | Tue |
| Southwest SWA1711 | 1:34p | 2h35m | Sun |
| United UAL2473 | 6:12p | 2h20m | Thu |
| United UAL2473 | 6:21p | 2h24m | Mon, Sat |
| United UAL2473 | 6:39p | 2h20m | Wed, Sun |
| United UAL2473 | 6:58p | 2h31m | Fri |
| United UAL2473 | 7:41p | 2h21m | Tue |
Allegiant
Southwest
UnitedThe route
One hop: DEN → TYSDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Denver (DEN) to Knoxville (TYS)
Denver International Airport (DEN) has 23 nonstop flights a week to Knoxville (TYS), operated by Allegiant, Southwest and United. No layovers, no connections — one hop out of DEN and you're there.
This route flies every day of the week, so any travel day works. Route data updated September 2026 from observed departures.
Route data updated September 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Denver to Knoxville?
The nonstop flight from Denver (DEN) to Knoxville (TYS) takes about 2h24m in the air, based on recently observed nonstop departures.
How long does it take to drive from Denver to Knoxville?
Driving from Denver to Knoxville takes about 19h 26m behind the wheel — roughly 1,335 miles, or about 2 days of real driving. The nonstop flight takes about 2h24m.