Direct flights from Buffalo to Chicago
21 nonstop flights a week on 1 airline. Zero layovers — one hop from BUF to MDW.
Flight time: about 1h12m nonstop
Which days does it fly?
When does it fly?
Departure times in Buffalo local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Southwest SWA205 | 7:26a | 1h12m | Sun |
| Southwest SWA4154 | 7:42a | 1h11m | Fri |
| Southwest SWA4154 | 7:50a | 1h12m | Mon, Thu |
| Southwest SWA3614 | 8:40a | 1h10m | Tue–Wed |
| Southwest SWA982 | 8:42a | 1h16m | Sat |
| Southwest SWA2125 | 12:59p | 1h12m | Sat |
| Southwest SWA484 | 1:27p | 1h14m | Sun |
| Southwest SWA766 | 2:59p | 1h19m | Wed |
| Southwest SWA766 | 3:15p | 1h7m | Tue |
| Southwest SWA766 | 4:18p | 1h15m | Fri |
| Southwest SWA766 | 4:32p | 1h8m | Mon |
| Southwest SWA766 | 5:44p | 1h14m | Thu |
| Southwest SWA1058 | 7:08p | 1h15m | Sat |
| Southwest SWA768 | 7:54p | 1h6m | Tue |
| Southwest SWA768 | 8:02p | 1h14m | Fri, Sun |
| Southwest SWA768 | 8:08p | 1h10m | Mon, Wed |
| Southwest SWA768 | 8:38p | 1h14m | Thu |
SouthwestThe route
One hop: BUF → MDWDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Buffalo (BUF) to Chicago (MDW)
Buffalo Niagara International Airport (BUF) has 21 nonstop flights a week to Chicago (MDW), operated by Southwest. No layovers, no connections — one hop out of BUF and you're there.
This route flies every day of the week, so any travel day works. Route data updated July 2026 from observed departures.
Route data updated July 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Buffalo to Chicago?
The nonstop flight from Buffalo (BUF) to Chicago (MDW) takes about 1h12m in the air, based on recently observed nonstop departures.
How long does it take to drive from Buffalo to Chicago?
Driving from Buffalo to Chicago takes about 8h 8m, covering roughly 533 miles. The nonstop flight takes about 1h12m.